5E5A
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
Summary for 5E5A
Entry DOI | 10.2210/pdb5e5a/pdb |
Descriptor | DNA (146-MER), Histone H3.2, Histone H4, ... (8 entities in total) |
Functional Keywords | ncp, ie1, hcmv, ctd, protein binding-viral protein-dna complex, protein binding/viral protein/dna |
Biological source | Homo sapiens (Humam) More |
Cellular location | Nucleus: P84233 P62799 P02281 |
Total number of polymer chains | 11 |
Total formula weight | 201100.70 |
Authors | |
Primary citation | Fang, Q.,Chen, P.,Wang, M.,Fang, J.,Yang, N.,Li, G.,Xu, R.M. Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome Elife, 5:-, 2016 Cited by PubMed: 26812545DOI: 10.7554/eLife.11911 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.809 Å) |
Structure validation
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