5DUI
Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter
Summary for 5DUI
Entry DOI | 10.2210/pdb5dui/pdb |
Descriptor | Forkhead box protein O1, DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), ... (4 entities in total) |
Functional Keywords | transcription factor, winged helix, dna binding, protein-dna complex, diabetes, transcription regulation, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q12778 |
Total number of polymer chains | 4 |
Total formula weight | 37771.29 |
Authors | Singh, P.,Endrizzi, J.A.,Chi, Y.-I. (deposition date: 2015-09-18, release date: 2016-09-21, Last modification date: 2023-09-27) |
Primary citation | Singh, P.,Han, E.H.,Endrizzi, J.A.,O'Brien, R.M.,Chi, Y.I. Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter. J. Struct. Biol., 198:54-64, 2017 Cited by PubMed: 28223045DOI: 10.1016/j.jsb.2017.02.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.306 Å) |
Structure validation
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