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5DUI

Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter

Summary for 5DUI
Entry DOI10.2210/pdb5dui/pdb
DescriptorForkhead box protein O1, DNA (5'-D(*TP*TP*TP*TP*CP*TP*AP*TP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*TP*CP*A)-3'), DNA (5'-D(*AP*TP*GP*AP*TP*TP*TP*AP*CP*GP*TP*AP*AP*AP*AP*TP*AP*GP*AP*AP*A)-3'), ... (4 entities in total)
Functional Keywordstranscription factor, winged helix, dna binding, protein-dna complex, diabetes, transcription regulation, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm : Q12778
Total number of polymer chains4
Total formula weight37771.29
Authors
Singh, P.,Endrizzi, J.A.,Chi, Y.-I. (deposition date: 2015-09-18, release date: 2016-09-21, Last modification date: 2023-09-27)
Primary citationSingh, P.,Han, E.H.,Endrizzi, J.A.,O'Brien, R.M.,Chi, Y.I.
Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter.
J. Struct. Biol., 198:54-64, 2017
Cited by
PubMed: 28223045
DOI: 10.1016/j.jsb.2017.02.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.306 Å)
Structure validation

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