5DG3

Structure of Pseudomonas aeruginosa LpxA in complex with UDP-3-O-(R-3-hydroxydecanoyl)-GlcNAc

Summary for 5DG3

Entry DOI	10.2210/pdb5dg3/pdb
Related	5DEM 5DEP
Descriptor	Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, uridine-5'-diphosphate-3-O-(R-3-hydroxydecanoyl)-N-acetyl-D-glucosamine, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	acyltransferases, catalytic domain, udp-glcnac, fatty acids, lipid a, substrate specificity, uridine diphosphate n-acetylglucosamine, hydrocarbon rulers, transferase
Biological source	Pseudomonas aeruginosa (strain PA7)
Cellular location	Cytoplasm : A6V1E4
Total number of polymer chains	6
Total formula weight	171497.76
Authors	Smith, E.W.,Chen, Y. (deposition date: 2015-08-27, release date: 2015-09-16, Last modification date: 2024-03-06)
Primary citation	Smith, E.W.,Zhang, X.,Behzadi, C.,Andrews, L.D.,Cohen, F.,Chen, Y. Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity. Biochemistry, 54:5937-5948, 2015 Cited by PubMed: 26352800 DOI: 10.1021/acs.biochem.5b00720 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation