5DF7
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AZLOCILLIN
Summary for 5DF7
Entry DOI | 10.2210/pdb5df7/pdb |
Related | 4KQO |
Descriptor | Cell division protein, (2R,4S)-5,5-dimethyl-2-[(1R)-2-oxo-1-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}ethyl]-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, ... (6 entities in total) |
Functional Keywords | azlocillin, beta-lactam antibiotics, acyl-enzyme complex, de-acylation, transferase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 123788.46 |
Authors | Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J. (deposition date: 2015-08-26, release date: 2016-01-13, Last modification date: 2024-01-10) |
Primary citation | Ren, J.,Nettleship, J.E.,Males, A.,Stuart, D.I.,Owens, R.J. Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590:288-297, 2016 Cited by PubMed: 26823174DOI: 10.1002/1873-3468.12054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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