5D8L
Human HSF2 DNA Binding Domain in complex with 3-site HSE DNA at 2.1 Angstroms Resolution
Summary for 5D8L
Entry DOI | 10.2210/pdb5d8l/pdb |
Related | 5D8K |
Descriptor | DNA (5'-D(P*GP*TP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 2, DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*AP*C)-3'), ... (4 entities in total) |
Functional Keywords | transcription factor, dna, hsf, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q03933 |
Total number of polymer chains | 8 |
Total formula weight | 73023.02 |
Authors | Jaeger, A.M.,Pemble, C.W.,Thiele, D.J. (deposition date: 2015-08-17, release date: 2016-01-06, Last modification date: 2024-03-06) |
Primary citation | Jaeger, A.M.,Pemble, C.W.,Sistonen, L.,Thiele, D.J. Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat.Struct.Mol.Biol., 23:147-154, 2016 Cited by PubMed: 26727490DOI: 10.1038/nsmb.3150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.069 Å) |
Structure validation
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