5D3I
Crystal structure of the SSL3-TLR2 complex
Summary for 5D3I
Entry DOI | 10.2210/pdb5d3i/pdb |
Related | 5D3D |
Descriptor | Toll-like receptor 2, Staphylococcal Superantigen-Like protein 3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | superantigens, superantigen-like proteins, ssl, ssl3, toll-like receptor 2, tlr2, tlr6, immunology, inflammation, inhibition, lipopeptide, phosphatidylcholine, pc, immune evasion, innate immunity, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 88156.46 |
Authors | Feitsma, L.J.,Huizinga, E.G. (deposition date: 2015-08-06, release date: 2015-08-19, Last modification date: 2024-05-01) |
Primary citation | Koymans, K.J.,Feitsma, L.J.,Brondijk, T.H.,Aerts, P.C.,Lukkien, E.,Lossl, P.,van Kessel, K.P.,de Haas, C.J.,van Strijp, J.A.,Huizinga, E.G. Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3). Proc.Natl.Acad.Sci.USA, 112:11018-11023, 2015 Cited by PubMed: 26283364DOI: 10.1073/pnas.1502026112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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