5CUM

Crystal structure of Human Defensin-5 Y27A mutant crystal form 1.

Summary for 5CUM

Entry DOI	10.2210/pdb5cum/pdb
Related	1ZMP 5CUI 5CUM
Descriptor	Defensin-5, CALCIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	paneth cells defensin, human alpha-defensin, intestinal defensin, antimicrobial protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	10939.48
Authors	Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2015-07-24, release date: 2016-07-27, Last modification date: 2023-09-27)
Primary citation	Xu, D.,Liao, C.,Zhang, B.,Tolbert, W.D.,He, W.,Dai, Z.,Zhang, W.,Yuan, W.,Pazgier, M.,Liu, J.,Yu, J.,Sansonetti, P.J.,Bevins, C.L.,Shao, Y.,Lu, W. Human Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion. Immunity, 2018 Cited by PubMed: 29858013 DOI: 10.1016/j.immuni.2018.04.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.752 Å)

Structure validation