5CSJ
S100B-RSK1 crystal structure B
Summary for 5CSJ
Entry DOI | 10.2210/pdb5csj/pdb |
Descriptor | Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | kinase, s100, inhibitor, signaling, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P04271 Nucleus: Q15418 |
Total number of polymer chains | 3 |
Total formula weight | 26648.52 |
Authors | Gogl, G.,Nyitray, L. (deposition date: 2015-07-23, release date: 2015-11-11, Last modification date: 2024-01-10) |
Primary citation | Gogl, G.,Alexa, A.,Kiss, B.,Katona, G.,Kovacs, M.,Bodor, A.,Remenyi, A.,Nyitray, L. Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY. J.Biol.Chem., 291:11-27, 2016 Cited by PubMed: 26527685DOI: 10.1074/jbc.M115.684928 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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