5CSG

The crystal structure of beta2-microglobulin R97Q mutant

Summary for 5CSG

• Entry DOI: 10.2210/pdb5csg/pdb
• Related: 2YXF
• Descriptor: Beta-2-microglobulin, ACETATE ION (3 entities in total)
• Functional Keywords: beta-2 microglobulin, amyloidosis, room temperature, immunoglobulin-like, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 11909.33

Authors

de Rosa, M.,Bolognesi, M.,Ricagno, S. (deposition date: 2015-07-23, release date: 2016-08-10, Last modification date: 2024-01-10)

• Primary citation: Le Marchand, T.,de Rosa, M.,Salvi, N.,Sala, B.M.,Andreas, L.B.,Barbet-Massin, E.,Sormanni, P.,Barbiroli, A.,Porcari, R.,Sousa Mota, C.,de Sanctis, D.,Bolognesi, M.,Emsley, L.,Bellotti, V.,Blackledge, M.,Camilloni, C.,Pintacuda, G.,Ricagno, S.; Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.; Nat Commun, 9:1658-1658, 2018; PubMed: 29695721; DOI: 10.1038/s41467-018-04078-y

Experimental method

X-RAY DIFFRACTION (1.5 Å)