5CGB
Crystal structure of FimH in complex with heptyl alpha-D-septanoside
Summary for 5CGB
Entry DOI | 10.2210/pdb5cgb/pdb |
Descriptor | Protein FimH, (6R)-1,6-anhydro-2-O-heptyl-6-(hydroxymethyl)-D-galactitol, SULFATE ION, ... (4 entities in total) |
Functional Keywords | uti, lectin, urinary tract infection, type 1 fimbriae, pilus, inhibitor, sugar binding protein |
Biological source | Escherichia coli K-12 |
Cellular location | Fimbrium: P08191 |
Total number of polymer chains | 2 |
Total formula weight | 34610.52 |
Authors | Jakob, R.P.,Preston, R.P.,Zihlmann, P.,Fiege, B.,Sager, C.P.,Vannam, R.,Rabbani, S.,Zalewski, A.,Maier, T.,Ernst, B.,Peczuh, M. (deposition date: 2015-07-09, release date: 2016-07-20, Last modification date: 2024-01-10) |
Primary citation | Sager, C.P.,Fiege, B.,Zihlmann, P.,Vannam, R.,Rabbani, S.,Jakob, R.P.,Preston, R.C.,Zalewski, A.,Maier, T.,Peczuh, M.W.,Ernst, B. The price of flexibility - a case study on septanoses as pyranose mimetics. Chem Sci, 9:646-654, 2018 Cited by PubMed: 29629131DOI: 10.1039/c7sc04289b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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