5CGB

Crystal structure of FimH in complex with heptyl alpha-D-septanoside

Summary for 5CGB

Entry DOI	10.2210/pdb5cgb/pdb
Descriptor	Protein FimH, (6R)-1,6-anhydro-2-O-heptyl-6-(hydroxymethyl)-D-galactitol, SULFATE ION, ... (4 entities in total)
Functional Keywords	uti, lectin, urinary tract infection, type 1 fimbriae, pilus, inhibitor, sugar binding protein
Biological source	Escherichia coli K-12
Cellular location	Fimbrium: P08191
Total number of polymer chains	2
Total formula weight	34610.52
Authors	Jakob, R.P.,Preston, R.P.,Zihlmann, P.,Fiege, B.,Sager, C.P.,Vannam, R.,Rabbani, S.,Zalewski, A.,Maier, T.,Ernst, B.,Peczuh, M. (deposition date: 2015-07-09, release date: 2016-07-20, Last modification date: 2024-01-10)
Primary citation	Sager, C.P.,Fiege, B.,Zihlmann, P.,Vannam, R.,Rabbani, S.,Jakob, R.P.,Preston, R.C.,Zalewski, A.,Maier, T.,Peczuh, M.W.,Ernst, B. The price of flexibility - a case study on septanoses as pyranose mimetics. Chem Sci, 9:646-654, 2018 Cited by PubMed: 29629131 DOI: 10.1039/c7sc04289b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation