5CCI
Structure of the Mg2+-bound synaptotagmin-1 SNARE complex (short unit cell form)
Summary for 5CCI
Entry DOI | 10.2210/pdb5cci/pdb |
Related | 5CCG 5CCH |
Descriptor | Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, ... (6 entities in total) |
Functional Keywords | synaptic fusion complex, synaptotagmin1, neuronal snare complex, endocytosis, exocytosis |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein: P63045 P32851 Cytoplasm, perinuclear region : P60881 P60881 Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21707 |
Total number of polymer chains | 6 |
Total formula weight | 96162.11 |
Authors | Zhou, Q.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Weis, W.I.,Brunger, A.T. (deposition date: 2015-07-02, release date: 2015-08-12, Last modification date: 2023-09-27) |
Primary citation | Zhou, Q.,Lai, Y.,Bacaj, T.,Zhao, M.,Lyubimov, A.Y.,Uervirojnangkoorn, M.,Zeldin, O.B.,Brewster, A.S.,Sauter, N.K.,Cohen, A.E.,Soltis, S.M.,Alonso-Mori, R.,Chollet, M.,Lemke, H.T.,Pfuetzner, R.A.,Choi, U.B.,Weis, W.I.,Diao, J.,Sudhof, T.C.,Brunger, A.T. Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525:62-67, 2015 Cited by PubMed: 26280336DOI: 10.1038/nature14975 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.1 Å) |
Structure validation
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