5C3G
Crystal structure of Bcl-xl bound to BIM-MM
Summary for 5C3G
| Entry DOI | 10.2210/pdb5c3g/pdb |
| Descriptor | Bcl-2-like protein 1,Bcl-2-like protein 1, Bcl-2-like protein 11 (3 entities in total) |
| Functional Keywords | complex, bcl-2 family, bh3, stapled peptide, apoptosis |
| Biological source | Mus musculus (House Mouse) More |
| Cellular location | Isoform Bcl-X(L): Mitochondrion inner membrane : Q07817 Endomembrane system ; Peripheral membrane protein . Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: O43521 |
| Total number of polymer chains | 2 |
| Total formula weight | 20117.53 |
| Authors | Miles, J.A.,Yeo, D.J.,Rowell, P.,Rodriguez-Marin, S.,Pask, C.M.,Warriner, S.L.,Edwards, T.A.,Wilson, A.J. (deposition date: 2015-06-17, release date: 2016-04-20, Last modification date: 2024-01-10) |
| Primary citation | Miles, J.A.,Yeo, D.J.,Rowell, P.,Rodriguez-Marin, S.,Pask, C.M.,Warriner, S.L.,Edwards, T.A.,Wilson, A.J. Hydrocarbon constrained peptides - understanding preorganisation and binding affinity. Chem Sci, 7:3694-3702, 2016 Cited by PubMed: 28970875DOI: 10.1039/c5sc04048e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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