5C17

Crystal structure of the mercury-bound form of MerB2

Summary for 5C17

• Entry DOI: 10.2210/pdb5c17/pdb
• Related: 3F0P 5C0T 5C0U 5DSF
• Descriptor: MerB2, MERCURY (II) ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: bacterial proteins, cysteine, lyases, mercury, lyase
• Biological source: Bacillus megaterium
• Total number of polymer chains: 1
• Total formula weight: 23716.80

Authors

Wahba, H.M.,Lecoq, L.,Stevenson, M.,Mansour, A.,Cappadocia, L.,Lafrance-Vanasse, J.,Wilkinson, K.J.,Sygusch, J.,Wilcox, D.E.,Omichinski, J.G. (deposition date: 2015-06-13, release date: 2016-02-03, Last modification date: 2023-09-27)

• Primary citation: Wahba, H.M.,Lecoq, L.,Stevenson, M.,Mansour, A.,Cappadocia, L.,Lafrance-Vanasse, J.,Wilkinson, K.J.,Sygusch, J.,Wilcox, D.E.,Omichinski, J.G.; Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.; Biochemistry, 55:1070-1081, 2016; PubMed: 26820485; DOI: 10.1021/acs.biochem.5b01298

Experimental method

X-RAY DIFFRACTION (1.24 Å)