5AA4

Crystal structure of MltF from Pseudomonas aeruginosa in complex with cell-wall tetrapeptide

Summary for 5AA4

• Entry DOI: 10.2210/pdb5aa4/pdb
• Related: 5AA1 5AA2 5AA3
• Descriptor: MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F, [6-[[(2~{R})-1-azanyl-1-oxidanylidene-propan-2-yl]amino]-6-oxidanylidene-5-[[(4~{R})-5-oxidanyl-5-oxidanylidene-4-[[(2~{S})-2-[[(2~{R})-2-oxidanylpropanoyl]amino]propanoyl]amino]pentanoyl]amino]hexyl]azanium, ... (4 entities in total)
• Functional Keywords: lyase, lytic transglycosilase, cell wall recycling
• Biological source: PSEUDOMONAS AERUGINOSA; More
• Total number of polymer chains: 4
• Total formula weight: 205003.17

Authors

Dominguez-Gil, T.,Acebron, I.,Hermoso, J.A. (deposition date: 2015-07-23, release date: 2016-10-12, Last modification date: 2024-01-10)

• Primary citation: Dominguez-Gil, T.,Lee, M.,Acebron-Avalos, I.,Mahasenan, K.V.,Hesek, D.,Dik, D.A.,Byun, B.,Lastochkin, E.,Fisher, J.F.,Mobashery, S.,Hermoso, J.A.; Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa.; Structure, 24:1729-1741, 2016; PubMed: 27618662; DOI: 10.1016/j.str.2016.07.019

Experimental method

X-RAY DIFFRACTION (2.4 Å)