5A63
Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution.
Replaces: 4UPCSummary for 5A63
Entry DOI | 10.2210/pdb5a63/pdb |
EMDB information | 3061 |
Descriptor | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... (8 entities in total) |
Functional Keywords | hydrolase, cryo-em, human gamma-secretase, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 177972.24 |
Authors | |
Primary citation | Bai, X.,Yan, C.,Yang, G.,Lu, P.,Ma, D.,Sun, L.,Zhou, R.,Scheres, S.H.W.,Shi, Y. An Atomic Structure of Human Gamma-Secretase Nature, 525:212-, 2015 Cited by PubMed: 26280335DOI: 10.1038/NATURE14892 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report