4ZRY
Crystal structure of the heterocomplex between coil 2B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10)
Summary for 4ZRY
Entry DOI | 10.2210/pdb4zry/pdb |
Descriptor | Keratin, type I cytoskeletal 10, Keratin, type II cytoskeletal 1 (2 entities in total) |
Functional Keywords | keratin, intermediate filament, coiled-coil, skin, protein-protein complex, epidermis, helix, protein fibril |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane : P04264 |
Total number of polymer chains | 2 |
Total formula weight | 28254.32 |
Authors | Bunick, C.G.,Steitz, T.A. (deposition date: 2015-05-12, release date: 2016-05-18, Last modification date: 2023-09-27) |
Primary citation | Bunick, C.G.,Milstone, L.M. The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease. J. Invest. Dermatol., 137:142-150, 2017 Cited by PubMed: 27595935DOI: 10.1016/j.jid.2016.08.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.30012502044 Å) |
Structure validation
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