4ZP3
AKAP18:PKA-RIIalpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA
Summary for 4ZP3
Entry DOI | 10.2210/pdb4zp3/pdb |
Descriptor | cAMP-dependent protein kinase type II-alpha regulatory subunit, A-kinase anchor protein 7 isoforms alpha and beta, CADMIUM ION, ... (4 entities in total) |
Functional Keywords | anchor points, amphiphathic helix, akap, dd-domain, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P13861 Isoform Alpha: Lateral cell membrane; Lipid- anchor. Isoform Beta: Apical cell membrane; Lipid- anchor: O43687 |
Total number of polymer chains | 18 |
Total formula weight | 87385.71 |
Authors | Goetz, F.,Roske, Y.,Faelber, K.,Zuehlke, K.,Autenrieth, K.,Kreuchwig, A.,Krause, G.,Herberg, F.W.,Daumke, O.,Heinemann, U.,Klussmann, E. (deposition date: 2015-05-07, release date: 2016-05-04, Last modification date: 2024-05-08) |
Primary citation | Gotz, F.,Roske, Y.,Schulz, M.S.,Autenrieth, K.,Bertinetti, D.,Faelber, K.,Zuhlke, K.,Kreuchwig, A.,Kennedy, E.J.,Krause, G.,Daumke, O.,Herberg, F.W.,Heinemann, U.,Klussmann, E. AKAP18:PKA-RII alpha structure reveals crucial anchor points for recognition of regulatory subunits of PKA. Biochem.J., 473:1881-1894, 2016 Cited by PubMed: 27102985DOI: 10.1042/BCJ20160242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.63 Å) |
Structure validation
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