4ZLR
Structure of the Brat-NHL domain bound to consensus RNA motif
Summary for 4ZLR
Entry DOI | 10.2210/pdb4zlr/pdb |
Descriptor | Brain tumor protein, RNA (5'-R(*UP*UP*GP*UP*UP*GP*UP*UP*UP*UP*UP*UP*UP*U)-3'), 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (7 entities in total) |
Functional Keywords | nhl-domain, beta-propeller, rna binding, translational repressor, translation |
Biological source | Drosophila melanogaster (Fruit fly) More |
Cellular location | Cytoplasm : Q8MQJ9 |
Total number of polymer chains | 3 |
Total formula weight | 70209.95 |
Authors | Jakob, L.,Treiber, N.,Treiber, T.,Stotz, M.,Loedige, I.,Meister, G. (deposition date: 2015-05-01, release date: 2015-11-11, Last modification date: 2024-01-10) |
Primary citation | Loedige, I.,Jakob, L.,Treiber, T.,Ray, D.,Stotz, M.,Treiber, N.,Hennig, J.,Cook, K.B.,Morris, Q.,Hughes, T.R.,Engelmann, J.C.,Krahn, M.P.,Meister, G. The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Rep, 13:1206-1220, 2015 Cited by PubMed: 26527002DOI: 10.1016/j.celrep.2015.09.068 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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