4Z87
Structure of the IMP dehydrogenase from Ashbya gossypii bound to GDP
Summary for 4Z87
Entry DOI | 10.2210/pdb4z87/pdb |
Descriptor | Inosine-5'-monophosphate dehydrogenase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | imp dehydrgoenase, bateman domain, oxidoreductase |
Biological source | Ashbya gossypii (strain ATCC 10895) |
Total number of polymer chains | 4 |
Total formula weight | 234398.66 |
Authors | Buey, R.M.,de Pereda, J.M.,Revuelta, J.L. (deposition date: 2015-04-08, release date: 2015-11-25, Last modification date: 2024-01-10) |
Primary citation | Buey, R.M.,Ledesma-Amaro, R.,Velazquez-Campoy, A.,Balsera, M.,Chagoyen, M.,de Pereda, J.M.,Revuelta, J.L. Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases. Nat Commun, 6:8923-8923, 2015 Cited by PubMed: 26558346DOI: 10.1038/ncomms9923 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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