4YVW

crystal structure of an enterovirus 71/coxsackievirus A16 chimeric virus-like particle

Summary for 4YVW

• Entry DOI: 10.2210/pdb4yvw/pdb
• Related: 4n43 4n53 4RQP 4RR3 4RS5 4YVS
• Descriptor: Capsid protein VP1, Capsid protein VP3, Capsid protein VP0 (3 entities in total)
• Functional Keywords: virus-like particle, neutralization epitope, virus
• Biological source: Enterovirus A71; More
• Cellular location: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : F6KTB0 F6KTB0 F6KTB0
• Total number of polymer chains: 15
• Total formula weight: 471229.90

Authors

Chen, R.,Lyu, K. (deposition date: 2015-03-20, release date: 2015-04-15, Last modification date: 2023-11-08)

• Primary citation: Lyu, K.,He, Y.L.,Li, H.Y.,Chen, R.; Crystal Structures of Yeast-Produced Enterovirus 71 and Enterovirus 71/Coxsackievirus A16 Chimeric Virus-Like Particles Provide the Structural Basis for Novel Vaccine Design against Hand-Foot-and-Mouth Disease; J.Virol., 89:6196-6208, 2015; PubMed: 25833050; DOI: 10.1128/JVI.00422-15

Experimental method

X-RAY DIFFRACTION (3.8 Å)