4YR8
Crystal structure of JNK in complex with a regulator protein
Summary for 4YR8
Entry DOI | 10.2210/pdb4yr8/pdb |
Descriptor | Mitogen-activated protein kinase 8, Dual specificity protein phosphatase 16, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | kinase domain, catalytic domain, transferase-hydrolase complex, transferase/hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P45983 Q9BY84 |
Total number of polymer chains | 8 |
Total formula weight | 247139.27 |
Authors | Liu, X.,Wang, J.,Wu, J.W.,Wang, Z.X. (deposition date: 2015-03-14, release date: 2016-03-16, Last modification date: 2023-11-08) |
Primary citation | Liu, X.,Zhang, C.S.,Lu, C.,Lin, S.C.,Wu, J.W.,Wang, Z.X. A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7:10879-10879, 2016 Cited by PubMed: 26988444DOI: 10.1038/ncomms10879 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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