4YON
P-Rex1:Rac1 complex
Summary for 4YON
Entry DOI | 10.2210/pdb4yon/pdb |
Descriptor | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1 (3 entities in total) |
Functional Keywords | protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 65538.19 |
Authors | Lucato, C.M.,Whisstock, J.C.,Ellisdon, A.M. (deposition date: 2015-03-11, release date: 2015-07-01, Last modification date: 2023-09-27) |
Primary citation | Lucato, C.M.,Halls, M.L.,Ooms, L.M.,Liu, H.J.,Mitchell, C.A.,Whisstock, J.C.,Ellisdon, A.M. The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells. J.Biol.Chem., 290:20827-20840, 2015 Cited by PubMed: 26112412DOI: 10.1074/jbc.M115.660456 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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