4Y4M

Thiazole synthase Thi4 from Methanocaldococcus jannaschii

Summary for 4Y4M

• Entry DOI: 10.2210/pdb4y4m/pdb
• Related: 4Y4L 4Y4N
• Descriptor: Putative ribose 1,5-bisphosphate isomerase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R)-2,3,5-tris(oxidanyl)-4-oxidanylidene-pentyl] hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (4 entities in total)
• Functional Keywords: thiazole synthase, isomerase, biosynthetic protein
• Biological source: Methanocaldococcus jannaschii
• Total number of polymer chains: 8
• Total formula weight: 256480.71

Authors

Zhang, X.,Ealick, S.E. (deposition date: 2015-02-10, release date: 2016-03-09, Last modification date: 2023-09-27)

• Primary citation: Zhang, X.,Eser, B.E.,Chanani, P.K.,Begley, T.P.,Ealick, S.E.; Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.; Biochemistry, 55:1826-1838, 2016; PubMed: 26919468; DOI: 10.1021/acs.biochem.6b00030

Experimental method

X-RAY DIFFRACTION (2.71 Å)