4XZU
Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody
Summary for 4XZU
Entry DOI | 10.2210/pdb4xzu/pdb |
Descriptor | 3E6 antibody Fab heavy chain, 3E6 antibody Fab light chain, Coagulation factor VIII, ... (5 entities in total) |
Functional Keywords | immunoglobulin, blood coagulation, antibody, discoidin, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 128785.09 |
Authors | Spiegel, P.C.,Wuerth, M.E. (deposition date: 2015-02-05, release date: 2015-12-09, Last modification date: 2019-12-04) |
Primary citation | Wuerth, M.E.,Cragerud, R.K.,Clint Spiegel, P. Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody. Sci Rep, 5:17216-17216, 2015 Cited by PubMed: 26598467DOI: 10.1038/srep17216 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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