4XVZ

MycF mycinamicin III 3'-O-methyltransferase in complex with Mg

Summary for 4XVZ

• Entry DOI: 10.2210/pdb4xvz/pdb
• Related: 4XVY
• Descriptor: Mycinamicin III 3''-O-methyltransferase, CHLORIDE ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: macrolide, methyltransferase, antibiotic, natural product, transferase
• Biological source: Micromonospora griseorubida
• Total number of polymer chains: 4
• Total formula weight: 128897.68

Authors

Akey, D.L.,Smith, J.L. (deposition date: 2015-01-28, release date: 2015-03-04, Last modification date: 2017-11-22)

• Primary citation: Bernard, S.M.,Akey, D.L.,Tripathi, A.,Park, S.R.,Konwerski, J.R.,Anzai, Y.,Li, S.,Kato, F.,Sherman, D.H.,Smith, J.L.; Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.; Acs Chem.Biol., 10:1340-1351, 2015; PubMed: 25692963; DOI: 10.1021/cb5009348

Experimental method

X-RAY DIFFRACTION (2.49 Å)