4XLW
Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)
Summary for 4XLW
Entry DOI | 10.2210/pdb4xlw/pdb |
Related | 4XL1 |
Descriptor | Neurogenic locus notch homolog protein 1, Delta-like protein, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | glycosylation, egf domains, receptor-ligand complex, protein binding |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 8 |
Total formula weight | 175246.31 |
Authors | Luca, V.C.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-01-13, release date: 2015-03-04, Last modification date: 2020-07-29) |
Primary citation | Luca, V.C.,Jude, K.M.,Pierce, N.W.,Nachury, M.V.,Fischer, S.,Garcia, K.C. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science, 347:847-853, 2015 Cited by PubMed: 25700513DOI: 10.1126/science.1261093 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.39 Å) |
Structure validation
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