4XLI
Crystal structure of Abl2/Arg kinase in complex with dasatinib
Summary for 4XLI
| Entry DOI | 10.2210/pdb4xli/pdb |
| Descriptor | Non-specific protein-tyrosine kinase, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, ZINC ION, ... (4 entities in total) |
| Functional Keywords | transferase, inhibitor, kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 62580.09 |
| Authors | Ha, B.H.,Boggon, T.J. (deposition date: 2015-01-13, release date: 2015-04-01, Last modification date: 2023-09-27) |
| Primary citation | Ha, B.H.,Simpson, M.A.,Koleske, A.J.,Boggon, T.J. Structure of the ABL2/ARG kinase in complex with dasatinib. Acta Crystallogr.,Sect.F, 71:443-448, 2015 Cited by PubMed: 25849507DOI: 10.1107/S2053230X15004793 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
