4XJK
Crystal structure of Mn(II) Ca(II) Na(I) bound calprotectin
Summary for 4XJK
Entry DOI | 10.2210/pdb4xjk/pdb |
Descriptor | Protein S100-A8, Protein S100-A9, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | ef-hand calcium binding, metal ion binding, immune system process, inflammatory response, metal binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 121332.46 |
Authors | Drennan, C.L.,Bowman, S.E.J. (deposition date: 2015-01-08, release date: 2015-04-15, Last modification date: 2023-09-27) |
Primary citation | Gagnon, D.M.,Brophy, M.B.,Bowman, S.E.,Stich, T.A.,Drennan, C.L.,Britt, R.D.,Nolan, E.M. Manganese Binding Properties of Human Calprotectin under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis. J.Am.Chem.Soc., 137:3004-3016, 2015 Cited by PubMed: 25597447DOI: 10.1021/ja512204s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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