4XHU

The complex structure of Timeless_PAB and PARP-1_catalytic domain

Summary for 4XHU

• Entry DOI: 10.2210/pdb4xhu/pdb
• Related: 4XHT 4XHW
• Descriptor: Poly [ADP-ribose] polymerase 1, Protein timeless homolog, GLYCEROL, ... (6 entities in total)
• Functional Keywords: dna damage response, transferase-replication complex, transferase/replication
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P09874 Q9UNS1
• Total number of polymer chains: 4
• Total formula weight: 103896.36

Authors

Xie, S.,Qian, C. (deposition date: 2015-01-06, release date: 2015-09-30, Last modification date: 2023-11-08)

• Primary citation: Xie, S.,Mortusewicz, O.,Ma, H.T.,Herr, P.,Poon, R.R.,Helleday, T.,Qian, C.; Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair.; Mol.Cell, 60:163-176, 2015; PubMed: 26344098; DOI: 10.1016/j.molcel.2015.07.031

Experimental method

X-RAY DIFFRACTION (2.089 Å)