4X6Z

Yeast 20S proteasome in complex with PR-VI modulator

Summary for 4X6Z

• Entry DOI: 10.2210/pdb4x6z/pdb
• Descriptor: Proteasome subunit beta type-6, Proteasome subunit beta type-1, Proteasome subunit beta type-2, ... (19 entities in total)
• Functional Keywords: 20s proteasome, low-molecular mass activators, allosteric regulation, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Cellular location: Cytoplasm: P23724 P38624 P25043 P25451 P22141 P30656 P30657 P21243 P23639 P23638 P40303 P32379 P40302 P21242
• Total number of polymer chains: 30
• Total formula weight: 776078.35

Authors

Rostankowski, R.,Witkowska, J.,Borek, D.,Otwinowski, Z.,Jankowska, E. (deposition date: 2014-12-09, release date: 2015-12-23, Last modification date: 2024-01-10)

• Primary citation: Witkowska, J.,Rostankowski, R.,Dubin, G.,Grudnik, P.,Golik, P.,Gaczynska, M.,Osmulski, P.,Borek, D.,Otwinowski, Z.,Jankowska, E.; Crystal structures revealed the common place of binding of low-molecular mass activators with the 20S proteasome; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)