4WUR
The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
Summary for 4WUR
Entry DOI | 10.2210/pdb4wur/pdb |
Related | 4P16 |
Descriptor | Papain-like protease, Polyubiquitin-B, ISOPROPYL ALCOHOL, ... (4 entities in total) |
Functional Keywords | mers-cov, papain-like protease, ubiquitin, complex, hydrolase |
Biological source | Human coronavirus EMC (HCoV-EMC) More |
Cellular location | Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : K9N7C7 Ubiquitin: Cytoplasm : P0CG47 |
Total number of polymer chains | 2 |
Total formula weight | 44917.97 |
Authors | Lei, J.,Hilgenfeld, R. (deposition date: 2014-11-03, release date: 2014-11-26, Last modification date: 2024-01-10) |
Primary citation | Lei, J.,Hilgenfeld, R. Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin. Virol Sin, 31:288-299, 2016 Cited by PubMed: 27245450DOI: 10.1007/s12250-016-3742-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.16 Å) |
Structure validation
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