4WQO

Structure of VHL-EloB-EloC-Cul2

Summary for 4WQO

Entry DOI	10.2210/pdb4wqo/pdb
Descriptor	Von Hippel-Lindau disease tumor suppressor, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total)
Functional Keywords	e3 ligase complex, transcription
Biological source	Homo sapiens (Human) More
Cellular location	Isoform 1: Cytoplasm. Isoform 3: Cytoplasm: P40337 Nucleus : Q15370 Q15369
Total number of polymer chains	4
Total formula weight	72474.79
Authors	Nguyen, H.C.,Xiong, Y. (deposition date: 2014-10-22, release date: 2015-03-04, Last modification date: 2023-09-27)
Primary citation	Nguyen, H.C.,Yang, H.,Fribourgh, J.L.,Wolfe, L.S.,Xiong, Y. Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex. Structure, 23:441-449, 2015 Cited by PubMed: 25661653 DOI: 10.1016/j.str.2014.12.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation