4WLJ

High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate

Summary for 4WLJ

• Entry DOI: 10.2210/pdb4wlj/pdb
• Related: 4WLH
• Descriptor: Kynurenine--oxoglutarate transaminase 1, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: lysine modification, transaminase, aminotransferase, alpha beta protein ligand, aoaa, deoxy aminopyridoxal phosphate, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q16773
• Total number of polymer chains: 2
• Total formula weight: 96500.17

Authors

Nadvi, N.A.,Salam, N.K.,Park, J.,Akladios, F.N.,Kapoor, V.,Collyer, C.A.,Gorrell, M.D.,Church, W.B. (deposition date: 2014-10-07, release date: 2014-12-03, Last modification date: 2023-09-27)

• Primary citation: Nadvi, N.A.,Salam, N.K.,Park, J.,Akladios, F.N.,Kapoor, V.,Collyer, C.A.,Gorrell, M.D.,Church, W.B.; High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate.; Protein Sci., 26:727-736, 2017; PubMed: 28097769; DOI: 10.1002/pro.3119

Experimental method

X-RAY DIFFRACTION (1.54 Å)