4WH9
Structure of the CDC25B Phosphatase Catalytic Domain with Bound Inhibitor
Summary for 4WH9
Entry DOI | 10.2210/pdb4wh9/pdb |
Related | 4WH7 |
Descriptor | M-phase inducer phosphatase 2, 2-[(2-cyano-3-fluoro-5-hydroxyphenyl)sulfanyl]ethanesulfonic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | phosphatase, inhibitor, fragment, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 22203.06 |
Authors | Lund, G.L.,Dudkin, S.,Borkin, D.,Ni, W.,Grembecka, J.,Cierpicki, T. (deposition date: 2014-09-20, release date: 2014-12-10, Last modification date: 2023-09-27) |
Primary citation | Lund, G.,Dudkin, S.,Borkin, D.,Ni, W.,Grembecka, J.,Cierpicki, T. Inhibition of CDC25B Phosphatase Through Disruption of Protein-Protein Interaction. Acs Chem.Biol., 10:390-394, 2015 Cited by PubMed: 25423142DOI: 10.1021/cb500883h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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