4V8A
The structure of thermorubin in complex with the 70S ribosome from Thermus thermophilus.
This is a non-PDB format compatible entry.
Summary for 4V8A
Entry DOI | 10.2210/pdb4v8a/pdb |
Descriptor | 23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (53 entities in total) |
Functional Keywords | ribosome, protein synthesis, thermorubin, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 102 |
Total formula weight | 4328287.91 |
Authors | Bulkley, D.,Johnson, F.A.,Steitz, T.A. (deposition date: 2011-12-05, release date: 2014-07-09, Last modification date: 2014-12-10) |
Primary citation | Bulkley, D.,Johnson, F.,Steitz, T.A. The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge b2a of the ribosome. J.Mol.Biol., 416:571-578, 2012 Cited by PubMed: 22240456DOI: 10.1016/j.jmb.2011.12.055 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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