4V6B
Crystal structure of human ferritin Phe167SerfsX26 mutant.
This is a non-PDB format compatible entry.
Summary for 4V6B
Entry DOI | 10.2210/pdb4v6b/pdb |
Descriptor | Ferritin, CALCIUM ION (3 entities in total) |
Functional Keywords | iron storage protein, disorder, iron, iron storage, metal-binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 144 |
Total formula weight | 3095371.92 |
Authors | Hurley, T.D.,Vidal, R. (deposition date: 2009-06-19, release date: 2014-07-09, Last modification date: 2023-09-20) |
Primary citation | Baraibar, M.A.,Muhoberac, B.B.,Garringer, H.J.,Hurley, T.D.,Vidal, R. Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration J.Biol.Chem., 285:1950-1956, 2010 Cited by PubMed: 19923220DOI: 10.1074/jbc.M109.042986 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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