4V2O
Structure of saposin B in complex with chloroquine
Summary for 4V2O
Entry DOI | 10.2210/pdb4v2o/pdb |
Descriptor | SAPOSIN-B, N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE (3 entities in total) |
Functional Keywords | hydrolase activator, protein-ligand complex |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Lysosome . Prosaposin: Secreted: P07602 |
Total number of polymer chains | 3 |
Total formula weight | 27932.10 |
Authors | Zubieta, C.,Lai, X.,Doyle, R.P. (deposition date: 2014-10-13, release date: 2015-12-09, Last modification date: 2024-01-10) |
Primary citation | Huta, B.P.,Mehlenbacher, M.R.,Nie, Y.,Lai, X.,Zubieta, C.,Bou-Abdallah, F.,Doyle, R.P. The Lysosomal Protein Saposin B Binds Chloroquine. Chemmedchem, 11:277-, 2016 Cited by PubMed: 26616259DOI: 10.1002/CMDC.201500494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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