4V11

Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84

Summary for 4V11

• Entry DOI: 10.2210/pdb4v11/pdb
• Descriptor: SYNAPTOTAGMIN-1, SYNAPTIC VESICLE GLYCOPROTEIN 2A, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: signaling protein
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein : P21579; Cell junction, synapse : Q7L0J3
• Total number of polymer chains: 2
• Total formula weight: 18463.23

Authors

Zhang, N.,Gordon, S.L.,Fritsch, M.J.,Esoof, N.,Campbell, D.,Gourlay, R.,Velupillai, S.,Macartney, T.,Peggie, M.,vanAalten, D.M.F.,Cousin, M.A.,Alessi, D.R. (deposition date: 2014-09-22, release date: 2015-02-25, Last modification date: 2024-01-10)

• Primary citation: Zhang, N.,Gordon, S.L.,Fritsch, M.J.,Esoof, N.,Campbell, D.G.,Gourlay, R.,Velupillai, S.,Macartney, T.,Peggie, M.,Van Aalten, D.M.F.,Cousin, M.A.,Alessi, D.R.; Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.; J.Neurosci., 35:2492-, 2015; PubMed: 25673844; DOI: 10.1523/JNEUROSCI.4248-14.2015

Experimental method

X-RAY DIFFRACTION (1.95 Å)