4V08

Inhibited dimeric pseudorabies virus protease pUL26N at 2 A resolution

Summary for 4V08

• Entry DOI: 10.2210/pdb4v08/pdb
• Related: 4CX8 4V07 4V0T
• Descriptor: UL26, DIISOPROPYL PHOSPHONATE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: viral protein, assemblin, ul26, ul26p, serine protease, protease, suid, prv, herpes, herpes virus
• Biological source: SUID HERPESVIRUS 1 (PSEUDORABIES VIRUS)
• Cellular location: Capsid scaffolding protein: Host cytoplasm . Assemblin: Host nucleus . Assembly protein: Host nucleus : Q83417
• Total number of polymer chains: 2
• Total formula weight: 53753.69

Authors

Zuehlsdorf, M.,Werten, S.,Palm, G.J.,Hinrichs, W. (deposition date: 2014-09-11, release date: 2015-07-15, Last modification date: 2024-01-10)

• Primary citation: Zuehlsdorf, M.,Werten, S.,Klupp, B.G.,Palm, G.J.,Mettenleiter, T.,Hinrichs, W.; Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease; Plos Pathog., 11:5045-, 2015; PubMed: 26161660; DOI: 10.1371/JOURNAL.PPAT.1005045

Experimental method

X-RAY DIFFRACTION (2.03 Å)