4UZ5
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM IV - 2.1A
Summary for 4UZ5
Entry DOI | 10.2210/pdb4uz5/pdb |
Related | 4UYU 4UYW 4UYZ 4UZ1 4UZ6 4UZ7 4UZ9 4UZA 4UZJ 4UZK 4UZL 4UZQ |
Descriptor | NOTUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | hydrolase, esterase, extracellular, alpha/beta hydrolase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted : Q6P988 |
Total number of polymer chains | 1 |
Total formula weight | 43823.81 |
Authors | Zebisch, M.,Jones, E.Y. (deposition date: 2014-09-04, release date: 2015-02-25, Last modification date: 2020-07-29) |
Primary citation | Kakugawa, S.,Langton, P.F.,Zebisch, M.,Howell, S.A.,Chang, T.,Liu, Y.,Feizi, T.,Bineva, G.,O'Reilly, N.,Snijders, A.P.,Jones, E.Y.,Vincent, J. Notum Deacylates Wnt Proteins to Suppress Signalling Activity. Nature, 519:187-, 2015 Cited by PubMed: 25731175DOI: 10.1038/NATURE14259 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report