4UV0

Structure of a semisynthetic phosphorylated DAPK

Summary for 4UV0

• Entry DOI: 10.2210/pdb4uv0/pdb
• Descriptor: DEATH-ASSOCIATED PROTEIN KINASE 1, TRIETHYLENE GLYCOL (3 entities in total)
• Functional Keywords: transferase, phosphoprotein, serine/threonine-protein kinase, native chemical ligation, calmodulin-binding, nucleotide-binding, apoptosis
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: P53355
• Total number of polymer chains: 1
• Total formula weight: 37320.86

Authors

de Diego, I.,Rios, P.,Meyer, C.,Koehn, M.,Wilmanns, M. (deposition date: 2014-08-01, release date: 2015-08-12, Last modification date: 2024-01-10)

• Primary citation: Temmerman, K.,Mertens, H.,Rios, P.,Simon, B.,Huart, A.S.,Piljic, A.,De Diego, I.,Svergun, D.,Schultz, C.,Koehn, M.,Wilmanns, M.; Molecular Mechanisms Behind Dapk Regulation: How the Phosphorylation Activity Switch Works; To be Published,

Experimental method

X-RAY DIFFRACTION (2.49 Å)