4UP1
Crystal structure of native human Thymidylate synthase in active form
Summary for 4UP1
| Entry DOI | 10.2210/pdb4up1/pdb |
| Related | 4UP2 |
| Descriptor | THYMIDYLATE SYNTHASE, SULFATE ION (2 entities in total) |
| Functional Keywords | transferase, low-salt conditions |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Nucleus : P04818 |
| Total number of polymer chains | 4 |
| Total formula weight | 144268.68 |
| Authors | Deschamps, P.,Rety, S.,Leulliot, N. (deposition date: 2014-06-11, release date: 2015-06-24, Last modification date: 2024-01-10) |
| Primary citation | Deschamps, P.,Rety, S.,Bareille, J.,Leulliot, N. Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates. Acta Crystallogr F Struct Biol Commun, 73:336-341, 2017 Cited by PubMed: 28580921DOI: 10.1107/S2053230X17007233 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.991 Å) |
Structure validation
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