4UOE
Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Deoxy-5'-Methylioadenosine and 4-Aminomethylaniline
Replaces: 4BNOSummary for 4UOE
Entry DOI | 10.2210/pdb4uoe/pdb |
Descriptor | SPERMIDINE SYNTHASE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 4-(aminomethyl)aniline, ... (6 entities in total) |
Functional Keywords | transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold |
Biological source | PLASMODIUM FALCIPARUM |
Total number of polymer chains | 3 |
Total formula weight | 97926.06 |
Authors | Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Person, L. (deposition date: 2014-06-03, release date: 2014-10-08, Last modification date: 2024-01-10) |
Primary citation | Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S. Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71:484-, 2015 Cited by PubMed: 25760598DOI: 10.1107/S1399004714027011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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