4UMN
Structure of a stapled peptide antagonist bound to Nutlin-resistant Mdm2.
Summary for 4UMN
Entry DOI | 10.2210/pdb4umn/pdb |
Descriptor | E3 ubiquitin-protein ligase Mdm2, M06 (3 entities in total) |
Functional Keywords | cell cycle |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 30154.52 |
Authors | Chee, S.,Wongsantichon, J.,Quah, S.,Robinson, R.C.,Verma, C.,Lane, D.P.,Brown, C.J.,Ghadessy, F.J. (deposition date: 2014-05-20, release date: 2014-05-28, Last modification date: 2024-02-07) |
Primary citation | Chee, S.M.,Wongsantichon, J.,Soo Tng, Q.,Robinson, R.,Joseph, T.L.,Verma, C.,Lane, D.P.,Brown, C.J.,Ghadessy, F.J. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2. PLoS ONE, 9:e104914-e104914, 2014 Cited by PubMed: 25115702DOI: 10.1371/journal.pone.0104914 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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