4UE1
Structure of the stapled peptide YS-01 bound to MDM2
Summary for 4UE1
Entry DOI | 10.2210/pdb4ue1/pdb |
Related | 4UD7 |
Descriptor | E3 UBIQUITIN-PROTEIN LIGASE MDM2, YS-01 (3 entities in total) |
Functional Keywords | ligase-peptide complex, ligase/peptide |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus, nucleoplasm: Q00987 |
Total number of polymer chains | 8 |
Total formula weight | 58619.08 |
Authors | Tan, Y.S.,Reeks, J.,Brown, C.J.,Jennings, C.E.,Eapen, R.S.,Tng, Q.S.,Thean, D.,Ying, Y.T.,Gago, F.J.F.,Lane, D.P.,Noble, M.E.M.,Verma, C. (deposition date: 2014-12-14, release date: 2016-01-13, Last modification date: 2023-12-20) |
Primary citation | Tan, Y.S.,Reeks, J.,Brown, C.J.,Thean, D.,Ferrer Gago, F.J.,Yuen, T.Y.,Goh, E.T.,Lee, X.E.,Jennings, C.E.,Joseph, T.L.,Lakshminarayanan, R.,Lane, D.P.,Noble, M.E.,Verma, C.S. Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design. J Phys Chem Lett, 7:3452-3457, 2016 Cited by PubMed: 27532490DOI: 10.1021/acs.jpclett.6b01525 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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