4U97
Crystal Structure of Asymmetric IRAK4 Dimer
Summary for 4U97
Entry DOI | 10.2210/pdb4u97/pdb |
Related | 4U9A |
Descriptor | Interleukin-1 receptor-associated kinase 4, STAUROSPORINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | kinase, autophosphorylation, dimer, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: Q9NWZ3 |
Total number of polymer chains | 2 |
Total formula weight | 70862.19 |
Authors | Ferrao, R.,Wu, H. (deposition date: 2014-08-05, release date: 2014-09-24, Last modification date: 2023-12-27) |
Primary citation | Ferrao, R.,Zhou, H.,Shan, Y.,Liu, Q.,Li, Q.,Shaw, D.E.,Li, X.,Wu, H. IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly. Mol.Cell, 55:891-903, 2014 Cited by PubMed: 25201411DOI: 10.1016/j.molcel.2014.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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