4U0X

Structure of ADC-7 beta-lactamase in complex with boronic acid inhibitor S02030

Summary for 4U0X

Entry DOI	10.2210/pdb4u0x/pdb
Related	4U0T
Descriptor	ADC-7 beta-lactamase, 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	beta-lactamase, boronic acid inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Acinetobacter baumannii
Total number of polymer chains	4
Total formula weight	164100.66
Authors	Powers, R.A.,Wallar, B.J.,Swanson, H.C. (deposition date: 2014-07-14, release date: 2014-11-19, Last modification date: 2023-12-27)
Primary citation	Powers, R.A.,Swanson, H.C.,Taracila, M.A.,Florek, N.W.,Romagnoli, C.,Caselli, E.,Prati, F.,Bonomo, R.A.,Wallar, B.J. Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii. Biochemistry, 53:7670-7679, 2014 Cited by PubMed: 25380506 DOI: 10.1021/bi500887n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation