4U0G
Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist
Summary for 4U0G
| Entry DOI | 10.2210/pdb4u0g/pdb |
| Related PRD ID | PRD_002111 |
| Descriptor | ATP-dependent Clp protease proteolytic subunit 2, ATP-dependent Clp protease proteolytic subunit 1, ADEP-2B5Me, ... (7 entities in total) |
| Functional Keywords | hydrolase, peptidase, hydrolase-antibiotic complex, hydrolase/antibiotic |
| Biological source | Mycobacterium tuberculosis More |
| Total number of polymer chains | 42 |
| Total formula weight | 638038.19 |
| Authors | Schmitz, K.R.,Carney, D.W.,Sello, J.K.,Sauer, R.T. (deposition date: 2014-07-11, release date: 2014-10-08, Last modification date: 2023-11-15) |
| Primary citation | Schmitz, K.R.,Carney, D.W.,Sello, J.K.,Sauer, R.T. Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery. Proc.Natl.Acad.Sci.USA, 111:E4587-E4595, 2014 Cited by PubMed: 25267638DOI: 10.1073/pnas.1417120111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1978 Å) |
Structure validation
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